SCHEMBL30947787

SCHEMBL30947787

CCn1nc(C)cc1C(=O)Nc1nc2cc(C(N)=O)cc(OCCCNC(=O)OC(C)(C)C)c2n1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 1.00
CYP3A4 P08684 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29240412 1.00 STING1 (1.00) STING1CYP3A4
SCHEMBL29240454 0.98 STING1 (0.96) STING1CYP3A4
SCHEMBL30947783 0.98 STING1 (0.96) STING1CYP3A4
SCHEMBL22857868 0.92 STING1 (0.85) STING1CYP3A4
SCHEMBL22857824 0.90 STING1 (0.82) STING1CYP3A4
SCHEMBL25098277 0.88 STING1 (0.90) STING1CYP3A4
SCHEMBL30206910 0.88 STING1 (1.00) STING1CYP3A4
SCHEMBL30207066 0.88 STING1 (0.90) STING1CYP3A4
SCHEMBL25098273 0.88 STING1 (1.00) STING1CYP3A4
SCHEMBL31318198 0.87 STING1 (0.78) STING1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118265545-A Asymmetric bisbenzimidazole STING agonist immunoconjugates and uses thereof 博尔特生物治疗药物有限公司 2024-06-28 CN disclosed