Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28921815 | 1.00 | EGFR (0.59) | EGFR | |
| SCHEMBL28650746 | 0.91 | EGFR (0.59) | EGFR | |
| SCHEMBL30948590 | 0.91 | EGFR (0.59) | EGFR | |
| SCHEMBL23462612 | 0.87 | EGFR (0.62) | EGFR | |
| SCHEMBL30626530 | 0.87 | EGFR (0.59) | EGFR | |
| SCHEMBL22804457 | 0.87 | EGFR (0.59) | EGFR | |
| SCHEMBL22520132 | 0.86 | EGFR (0.61) | EGFR | |
| SCHEMBL28614583 | 0.86 | EGFR (0.43) | EGFR | |
| SCHEMBL28650090 | 0.86 | EGFR (0.48) | EGFR | |
| SCHEMBL23421438 | 0.86 | EGFR (0.62) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113179640-B | Nitrogen-containing polycyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-113677680-B | EGFR inhibitor, composition and application thereof | 贝达药业股份有限公司 | 2024-05-10 | — | — | CN | disclosed |