SCHEMBL30949

SCHEMBL30949

C=CCC(N)C(=C)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 7/20 0.48
GRIK2 Q13002 5/20 0.48
GRM1 Q13255 1/20 0.40
GRM2 Q14416 1/20 0.40
CYP2C19 P33261 2/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
BLM P54132 1/20 0.34
SLC6A3 Q01959 1/20 0.34
MEN1 O00255 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
KMT2A Q03164 1/20 0.34
CPA1 P15085 1/20 0.34
ALDH1A1 P00352 1/20 0.31
ABCC4 O15439 1/20 0.31
MAPT P10636 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6436139 1.00 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2CYP2C19
Hydrochloric Acid SCHEMBL6447260 0.98 GRIK1 (0.47) GRIK1GRIK2GRM1GRM2CYP2C19
SCHEMBL17800678 0.83 GRIK1 (0.37) GRIK1GRIK2GRM1GRM2SLC6A2
SCHEMBL861484 0.78 GRIK1 (0.41) GRIK1GRIK2CYP2C19SLC6A2SLC6A4
SCHEMBL44428 0.78
SCHEMBL74086 0.78
SCHEMBL616036 0.78
SCHEMBL3258226 0.78 GRIK1 (0.38) GRIK1GRIK2TSHRALDH1A1MAPT
SCHEMBL1083274 0.77 GRIK1 (0.40) GRIK1GRIK2
SCHEMBL7173452 0.77 NPSR1 (0.40) GRIK1GRIK2CYP2C19MEN1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3236 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4294776-B1 CEMENTITIOUS COMPOSITION COMPRISING A POLYMERIC MICRO-GEL AS AN ANTI-GAS MIGRATION AGENT SNF GROUP (FR) 2024-06-26 EP claimed
CN-113769059-B Poly (zinc prasugrel) granule and preparation method thereof 北京鑫开元医药科技有限公司 2024-02-13 CN claimed
US-11833255-B2 Nanoparticles with pH triggered drug release THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2023-12-05 US claimed
US-11802173-B2 Voided latex particles containing functionalized outer shells ARKEMA INC. (US) 2023-10-31 US claimed
WO-2023161081-A1 WATERBORNE BIODEGRADABLE POLYMER COMPOSITION ORGANIK KIMYA SANAYI VE TIC. A.S. (TR) 2023-08-31 WO claimed
CN-114082938-B Metal particle and preparation method and application thereof 苏州艾美特企业管理有限公司 2023-08-25 CN claimed
EP-3337857-B1 UNIVERSAL PIGMENT PREPARATIONS FOR POINT-OF-SALE USE BASF SE (DE) 2023-08-09 EP claimed
EP-3845573-B1 COPOLYMER AND MEDICAL MATERIAL CONTAINING THE SAME TORAY INDUSTRIES (JP) 2023-08-09 EP claimed
EP-3999610-B1 USE OF NANOPARTICLE COMPOSITIONS AS HEAT TRANSFER FLUIDS IN BATTERY OR OTHER ELECTRICAL EQUIPMENT SYSTEMS EVONIK OPERATIONS GMBH (DE) 2023-06-28 EP claimed
EP-4119640-B1 LUBRICANT ADDITIVE COMPOSITION CONTAINING POLYALKYLMETHACRYLATES EVONIK OPERATIONS GMBH (DE) 2023-06-14 EP claimed
US-4615882-A NON ADSORBABLE ORGANOSILICON QUATERNARY AMMONIUM SALT BONDED TO WATER-SOLUBLE POLYMER STOCKEL RICHARD F 1986-10-07 US claimed
US-4572920-A ANION EXCHANGE MONOMER, ACRYLIC MONOMER FOR PREVENTION OF DENTAL CARIES RESEARCH CORPORATION (US) 1986-02-25 US claimed
EP-0013156-B1 PARTICULATE STRUCTURE AND ELEMENT FOR ANALYSIS OR TRANSPORT OF A LIQUID AND METHOD OF MAKING SAID ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-05-22 EP claimed
US-4515910-A SUSTAINED RELEASE OF FLUORIDE BY ION EXCHANGE; ANTICARIES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 1985-05-07 US claimed
US-4479879-A CATIONIC POLYMER FLOCCULANTS, ANIONIC POLYMER FLOCCULANTS KURITA WATER INDUSTRIES LTD. (JP) 1984-10-30 US claimed
US-4443565-A SOLUTION POLYMERIZATION, BLENDS, ATTENUATION MICROWAVES MITSUBISHI MONSANTO CHEMICAL COMPANY (JP) 1984-04-17 US claimed
EP-0102025-A2 Dry electrostatographic toner and process for its preparation Agfa-Gevaert AG (DE) 1984-03-07 EP claimed
US-4306955-A Photopolymerized acrylic polymer essentially devoid of residual monomer(s) RHONE-POULENC INDUSTRIES (FR) 1981-12-22 US claimed
EP-0006777-B1 A PROCESS FOR PREPARING POLYMERS USABLE AS FLOCCULANTS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1981-10-14 EP claimed
US-4135524-A FLUOROPOLYMER CONTAINING FLUOROALKYL METHACRYLATE, AMINOALKYLMETHACRYLATE AND ETHYLENEDIMETHACRYLATE CLAIROL INCORPORATED (US) 1979-01-23 US claimed