Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MARS1 | P56192 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.40 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4111468 | 1.00 | NPSR1 (0.69) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4098394 | 0.91 | NPSR1 (0.69) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30949040 | 0.91 | NPSR1 (0.69) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1047619 | 0.90 | CYP1A2 (0.55) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL998643 | 0.90 | CYP1A2 (0.55) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4103934 | 0.89 | NPSR1 (0.53) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1049483 | 0.88 | NPSR1 (0.53) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL24273139 | 0.86 | CYP1A2 (0.73) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14627450 | 0.85 | CYP1A2 (0.73) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1050322 | 0.84 | CYP1A2 (0.65) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118001272-A | Use of indazoles for treating diseases mediated by activation of inflammatory bodies | 中山大学 | 2024-05-10 | — | — | CN | claimed |
| CN-118001272-A | Use of indazoles for treating diseases mediated by activation of inflammatory bodies | 中山大学 | 2024-05-10 | — | — | CN | disclosed |