SCHEMBL30949482

SCHEMBL30949482

CC(C)=CCC(N=C(c1ccccc1)c1ccccc1)C(=O)OC(C)(C)C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 1/20 0.64
BTN3A1 O00481 2/20 0.38
ALDH1A1 P00352 4/20 0.36
KMT2A Q03164 4/20 0.36
SLC7A5 Q01650 1/20 0.36
CTSK P43235 1/20 0.35
TSHR P16473 3/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MEN1 O00255 3/20 0.34
POLB P06746 2/20 0.34
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.34
APAF1 O14727 1/20 0.34
TDP2 O95551 1/20 0.34
NSD2 O96028 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
THRB P10828 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30949485 1.00 AAK1 (0.64) AAK1BTN3A1ALDH1A1KMT2ASLC7A5
SCHEMBL22754553 0.86 AAK1 (0.65) AAK1BTN3A1ALDH1A1KMT2ASLC7A5
SCHEMBL22754552 0.86 AAK1 (0.65) AAK1BTN3A1ALDH1A1KMT2ASLC7A5
SCHEMBL22754571 0.86 AAK1 (0.65) AAK1BTN3A1ALDH1A1KMT2ASLC7A5
SCHEMBL17902787 0.85 AAK1 (0.64) AAK1BTN3A1ALDH1A1KMT2ASLC7A5
SCHEMBL5142674 0.84 MEN1 (0.44) AAK1BTN3A1ALDH1A1KMT2ATSHR
SCHEMBL30777019 0.83 AAK1 (0.68) AAK1BTN3A1ALDH1A1KMT2ASLC7A5
SCHEMBL2325860 0.82 AAK1 (0.71) AAK1BTN3A1ALDH1A1KMT2ASLC7A5
SCHEMBL24073054 0.82 AAK1 (0.64) AAK1BTN3A1ALDH1A1KMT2ASLC7A5
SCHEMBL24832134 0.82 AAK1 (0.67) AAK1ALDH1A1KMT2ASLC7A5CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005531-A Synthesis method of chiral unnatural amino acid derivative 内蒙古大学 2024-05-10 CN disclosed