Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.56 |
| ▸ | F10 | P00742 | 9/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.44 |
| ▸ | PLG | P00747 | 7/20 | 0.44 |
| ▸ | F2 | P00734 | 6/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21834083 | 1.00 | ESR1 (0.56) | ESR1ESR2F10PRSS1PRSS2 | |
| SCHEMBL31670428 | 0.88 | ESR1 (0.55) | ESR1ESR2F10PRSS1PRSS2 | |
| SCHEMBL4680153 | 0.84 | ESR1 (0.55) | ESR1ESR2F10PRSS1PRSS2 | |
| SCHEMBL4682332 | 0.81 | ESR1 (0.50) | ESR1ESR2F10PRSS1PRSS2 | |
| SCHEMBL28620925 | 0.81 | ESR1 (0.55) | ESR1ESR2ABHD6PKM | |
| SCHEMBL12862882 | 0.81 | ESR1 (0.67) | ESR1ESR2ABHD6PKMMAPT | |
| SCHEMBL31670363 | 0.79 | ESR1 (0.57) | ESR1ESR2F10ABHD6PKM | |
| SCHEMBL21834082 | 0.79 | ESR1 (0.57) | ESR1ESR2F10ABHD6PKM | |
| SCHEMBL31670427 | 0.78 | ESR1 (0.44) | ESR1ESR2F10PRSS1PRSS2 | |
| SCHEMBL8266789 | 0.77 | ESR1 (0.72) | ESR1ESR2ABHD6PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3852791-B1 | ACTIVATING PYRUVATE KINASE R | NOVO NORDISK HEALTHCARE AG (CH) | 2024-07-03 | — | — | EP | disclosed |