Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 13/20 | 0.59 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
| ▸ | WNT1 | P04628 | 4/20 | 0.42 |
| ▸ | CLK2 | P49760 | 2/20 | 0.42 |
| ▸ | CLK3 | P49761 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17664720 | 1.00 | BTK (0.59) | BTKIKBKETBK1WNT1CLK2 | |
| SCHEMBL17664654 | 0.84 | BTK (0.58) | BTKWNT1CLK2CLK3DYRK1A | |
| Hydrochloric Acid SCHEMBL30950566 | 0.83 | BTK (0.57) | BTKWNT1CLK2CLK3DYRK1A | |
| SCHEMBL30950546 | 0.80 | BTK (0.56) | BTK | |
| SCHEMBL17664722 | 0.80 | BTK (0.56) | BTK | |
| SCHEMBL17660349 | 0.72 | BTK (0.44) | BTK | |
| SCHEMBL17646039 | 0.70 | MGAT2 (0.47) | BTKCLK2CLK3DYRK1A | |
| SCHEMBL17646013 | 0.70 | MGAT2 (0.47) | BTKCLK2CLK3DYRK1A | |
| SCHEMBL19876272 | 0.69 | BTK (0.56) | BTK | |
| SCHEMBL17670765 | 0.68 | BTK (0.41) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129395-A1 | BTK INHIBITORS | GWYNANT THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |