Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27457768 | 1.00 | BTK (0.54) | BTKLCKKDM4EMAPTKMT2A | |
| SCHEMBL17645776 | 0.89 | BTK (0.67) | BTKLCK | |
| SCHEMBL30950500 | 0.89 | BTK (0.67) | BTKLCK | |
| SCHEMBL30950478 | 0.88 | BTK (0.50) | BTKLCKKDM4EMAPTKMT2A | |
| SCHEMBL30950434 | 0.88 | BTK (0.56) | BTKLCKKMT2A | |
| SCHEMBL27456675 | 0.88 | BTK (0.53) | BTKLCK | |
| SCHEMBL30950479 | 0.88 | BTK (0.53) | BTKLCK | |
| SCHEMBL27457649 | 0.88 | BTK (0.56) | BTKLCKKMT2A | |
| SCHEMBL30950455 | 0.81 | BTK (0.50) | BTKLCKKDM4EMAPTKMT2A | |
| SCHEMBL27458164 | 0.81 | BTK (0.50) | BTKLCKKDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129395-A1 | BTK INHIBITORS | GWYNANT THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |