SCHEMBL30951065

SCHEMBL30951065

CCCOC(=O)C1(C)CCc2c(C)c(O)c(C)c(C)c2O1

nearest known ligand 0.64

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.64
PTGS2 P35354 1/20 0.64
CYP1A2 P05177 1/20 0.64
CYP3A4 P08684 1/20 0.64
TSHR P16473 1/20 0.64
PSEN1 P49768 7/20 0.59
TTPA P49638 4/20 0.52
ALOX5 P09917 2/20 0.52
NR1I2 O75469 1/20 0.43
CAPN1 P07384 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29242846 1.00 PTGS1 (0.64) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL15851248 0.93 PSEN1 (0.66) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL30951066 0.93 PSEN1 (0.66) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL2393197 0.91 PTGS1 (0.68) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL30951067 0.91 PTGS1 (0.68) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL16207575 0.91 PSEN1 (0.72) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL16207664 0.91 PSEN1 (0.72) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL16207556 0.91 PSEN1 (0.72) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL16207663 0.91 PSEN1 (0.72) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL16207528 0.91 PSEN1 (0.72) PTGS1PTGS2CYP1A2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118126011-A Method for chiral resolution of Trolox and Trolox ester compound enantiomer 辽宁大学 2024-06-04 CN claimed
CN-118126011-A Method for chiral resolution of Trolox and Trolox ester compound enantiomer 辽宁大学 2024-06-04 CN disclosed