SCHEMBL30951540

SCHEMBL30951540

COc1ccc(-c2nn(-c3ccc4c(c3)CNCC4)c3c2cnc2ccccc23)cc1OC

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.56
▸ LMNA P02545 3/20 0.48
▸ PDE4A P27815 2/20 0.45
▸ PDE4B Q07343 2/20 0.45
▸ PDE4C Q08493 2/20 0.45
▸ PDE4D Q08499 2/20 0.45
▸ TP53 P04637 5/20 0.41
▸ POLB P06746 2/20 0.41
▸ PIK3CD O00329 1/20 0.38
▸ PIK3CA P42336 1/20 0.38
▸ PIK3CB P42338 1/20 0.38
▸ MTOR P42345 1/20 0.38
▸ PIK3CG P48736 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29254428 1.00 MAPT (0.56) MAPTLMNAPDE4APDE4BPDE4C
Hydrochloric Acid SCHEMBL30951569 0.99 MAPT (0.55) MAPTLMNAPDE4APDE4BPDE4C
Hydrochloric Acid SCHEMBL29254471 0.99 MAPT (0.55) MAPTLMNAPDE4APDE4BPDE4C
SCHEMBL30951538 0.97 MAPT (0.56) MAPTLMNAPDE4APDE4BPDE4C
SCHEMBL29254451 0.97 MAPT (0.56) MAPTLMNAPDE4APDE4BPDE4C
Hydrochloric Acid SCHEMBL30951589 0.96 MAPT (0.55) MAPTLMNAPDE4APDE4BPDE4C
SCHEMBL29254463 0.93 MAPT (0.60) MAPTLMNAPDE4APDE4BPDE4C
SCHEMBL30951513 0.93 MAPT (0.60) MAPTLMNAPDE4APDE4BPDE4C
Hydrochloric Acid SCHEMBL30951585 0.92 MAPT (0.59) MAPTLMNAPDE4APDE4BPDE4C
SCHEMBL30951514 0.90 MAPT (0.59) MAPTLMNAPDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118076605-A Substituted 1H-pyrazolo [4,3-c ] quinolines, methods of preparation and uses thereof 洛蒙治疗公司 2024-05-24 — — CN claimed
WO-2026080918-A1 SYNTHESIS OF A TETRAHYDROISOQUINOLIN-PYRAZOLOQUINOLIN COMPOUND AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF LOMOND THERAPEUTICS, INC. (US) 2026-04-16 — — WO disclosed
WO-2026080917-A1 POLYMORPHS AND SOLID FORMS OF A TETRAHYDROISOQUINOLINPYRAZOLOQUINOLIN COMPOUND, AND PHARMACEUTICAL COMPOSITIONS THEREOF LOMOND THERAPEUTICS, INC. (US) 2026-04-16 — — WO disclosed
CN-118076605-A Substituted 1H-pyrazolo [4,3-c ] quinolines, methods of preparation and uses thereof 洛蒙治疗公司 2024-05-24 — — CN disclosed
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