Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 12/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22440859 | 1.00 | PDK2 (0.61) | PDK2MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL9886708 | 0.86 | PDK2 (0.55) | PDK2 | |
| SCHEMBL16271512 | 0.86 | PDK2 (0.49) | PDK2 | |
| SCHEMBL30340691 | 0.85 | PDK2 (0.53) | PDK2KMT2A | |
| SCHEMBL30705226 | 0.85 | PDK2 (0.63) | PDK2 | |
| SCHEMBL236472 | 0.85 | PDK2 (0.63) | PDK2 | |
| SCHEMBL13269073 | 0.85 | PDK2 (0.53) | PDK2KMT2A | |
| SCHEMBL16271513 | 0.83 | PDK2 (0.47) | PDK2 | |
| SCHEMBL13045515 | 0.83 | PDK2 (0.52) | PDK2 | |
| SCHEMBL11926755 | 0.83 | PDK2 (0.47) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121084-A1 | PREPARATION OF NITRILES | MERCK PATENT GMBH (DE) | 2024-06-13 | — | — | WO | disclosed |