Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30951760 | 1.00 | POLB (0.40) | POLBALDH1A1KDM4ELRRK2MEN1 | |
| SCHEMBL31476290 | 1.00 | POLB (0.40) | POLBALDH1A1KDM4ELRRK2MEN1 | |
| SCHEMBL15868304 | 0.90 | POLB (0.42) | POLBALDH1A1MEN1NPC1STAT3 | |
| SCHEMBL24313964 | 0.88 | LRRK2 (0.30) | LRRK2 | |
| SCHEMBL14677434 | 0.87 | POLB (0.42) | POLBALDH1A1MEN1NPC1STAT3 | |
| SCHEMBL30951766 | 0.87 | POLB (0.40) | POLBALDH1A1KDM4E | |
| SCHEMBL30122283 | 0.87 | POLB (0.40) | POLBALDH1A1KDM4E | |
| SCHEMBL30122203 | 0.87 | POLB (0.40) | POLBALDH1A1KDM4E | |
| SCHEMBL17609333 | 0.85 | POLB (0.40) | POLBALDH1A1MEN1NPC1STAT3 | |
| SCHEMBL31476227 | 0.84 | LRRK2 (0.30) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630421-A1 | SYNTHESIS OF SULFOXIMINE COMPOUNDS HAVING A STEREOGENIC SULFUR ATOM | Syngenta Crop Protection AG (CH) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121335-A1 | SYNTHESIS OF SULFOXIMINE COMPOUNDS HAVING A STEREOGENIC SULFUR ATOM | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-13 | — | — | WO | disclosed |