SCHEMBL30951983

SCHEMBL30951983

NS(=O)(=O)c1ccc(C2(O)C(=O)N(Cc3ccc4c(c3)OCO4)c3ccccc32)cc1

nearest known ligand 0.78

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 17/20 0.78
ALDH1A1 P00352 3/20 0.60
USP2 O75604 2/20 0.60
MAPT P10636 2/20 0.60
ALOX15 P16050 1/20 0.60
TSHR P16473 1/20 0.60
HSD17B10 Q99714 1/20 0.60
KDM4E B2RXH2 1/20 0.57
MEN1 O00255 1/20 0.57
HTT P42858 1/20 0.57
KMT2A Q03164 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4728008 0.88 SCN9A (1.00) SCN9AALDH1A1USP2MAPTALOX15
SCHEMBL30951974 0.86 SCN9A (0.71) SCN9AALDH1A1USP2MAPTALOX15
SCHEMBL30951970 0.86 SCN9A (0.70) SCN9AALDH1A1USP2MAPTALOX15
SCHEMBL30951989 0.83 SCN9A (0.65) SCN9AALDH1A1USP2MAPTALOX15
SCHEMBL30951997 0.82 SCN9A (0.62) SCN9A
SCHEMBL30951988 0.82 SCN9A (0.60) SCN9A
SCHEMBL30951993 0.82 SCN9A (0.62) SCN9A
SCHEMBL4731135 0.81 SCN9A (1.00) SCN9A
SCHEMBL4597206 0.81 SCN9A (1.00) SCN9A
SCHEMBL4596011 0.80 SCN9A (0.84) SCN9AALDH1A1USP2MAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630401-A2 CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF Rutgers, the State University of New Jersey (US) 2025-10-15 EP disclosed
WO-2024124023-A2 CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-06-13 WO disclosed