Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30952648 | 0.81 | KMT2A (0.50) | KMT2ASLC6A4SLC6A2NOTUMTSHR | |
| SCHEMBL2283629 | 0.76 | KMT2A (0.47) | KMT2ASLC6A4SLC6A2NOTUMTSHR | |
| SCHEMBL526316 | 0.76 | NOTUM (0.49) | KMT2ASLC6A4SLC6A2NOTUMCYP1A2 | |
| SCHEMBL1967791 | 0.75 | SLC6A4 (0.47) | KMT2ASLC6A4SLC6A2NOTUMTSHR | |
| SCHEMBL29743218 | 0.75 | SLC6A4 (0.47) | KMT2ASLC6A4SLC6A2NOTUMTSHR | |
| SCHEMBL10203775 | 0.72 | NOTUM (0.53) | KMT2ASLC6A4SLC6A2NOTUMCYP1A2 | |
| SCHEMBL5851331 | 0.72 | KMT2A (0.50) | KMT2ASLC6A4SLC6A2NOTUMTSHR | |
| SCHEMBL11412911 | 0.72 | KMT2A (0.49) | KMT2ASLC6A4SLC6A2NOTUMTSHR | |
| SCHEMBL14683431 | 0.71 | NOTUM (0.47) | KMT2ASLC6A4SLC6A2NOTUMCYP1A2 | |
| SCHEMBL10165373 | 0.71 | NOTUM (0.47) | KMT2ASLC6A4SLC6A2NOTUMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140687-A1 | S1PR2 REGULATOR AND USE THEREOF | 北京昌平实验室 | 2024-07-04 | — | — | WO | disclosed |
| CN-118255830-A | S1PR2 modulators and uses thereof | 北京昌平实验室 | 2024-06-28 | — | — | CN | disclosed |