SCHEMBL30953020

SCHEMBL30953020

CC1CCC([C@H](NC(=O)c2ccnn2C)C(=O)Nc2cc([C@@H](C)N3C[C@@H](C(F)(F)F)NC3=O)ccn2)CC1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CDK2 P24941 2/20 0.32
▸ CBLB Q13191 4/20 0.31
▸ BUB1 O43683 1/20 0.31
▸ TBK1 Q9UHD2 2/20 0.31
▸ LMNA P02545 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ CCNE1 P24864 1/20 0.31
▸ GSK3B P49841 1/20 0.31
▸ IL17A Q16552 3/20 0.31
▸ MBOAT4 Q96T53 1/20 0.30
▸ CTSS P25774 1/20 0.30
▸ NPC1 O15118 2/20 0.30
▸ RAB9A P51151 2/20 0.30
▸ PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953094 0.92 IL17A (0.35) CBLBTBK1IL17A
SCHEMBL30953075 0.92 IL17A (0.38) CDK2BUB1TBK1LMNASMN1; SMN2
SCHEMBL30952924 0.91 MEN1 (0.33) CDK2LMNASMN1; SMN2CCNE1IL17A
SCHEMBL30953101 0.91 CDK2 (0.33) CDK2BUB1CCNE1GSK3BIL17A
SCHEMBL30952982 0.89 IL17A (0.40) CDK2CCNE1GSK3BIL17A
SCHEMBL30953011 0.87 IL17A (0.37) CDK2BUB1LMNASMN1; SMN2CCNE1
SCHEMBL30953003 0.86 IL17A (0.36) CBLBIL17A
SCHEMBL30953084 0.85 IL17A (0.40) CBLBIL17A
SCHEMBL30952976 0.84 IL17A (0.36) CDK2BUB1CCNE1GSK3BIL17A
SCHEMBL30953449 0.83 PIK3C3 (0.33) CBLBTBK1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP claimed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO claimed
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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