Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1192656 | 1.00 | ATR (0.50) | ATRGSK3BDYRK1ASYKTGFBR1 | |
| SCHEMBL828560 | 0.84 | TP53 (0.51) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL25600283 | 0.83 | JAK2 (0.52) | NPC1RAB9AAAK1JAK2JAK1 | |
| SCHEMBL29393227 | 0.83 | ATR (0.46) | ATRGSK3BDYRK1ATGFBR1IRAK4 | |
| SCHEMBL1133582 | 0.83 | ATR (0.46) | ATRGSK3BDYRK1ATGFBR1IRAK4 | |
| SCHEMBL29402022 | 0.83 | ATR (0.46) | ATRGSK3BDYRK1ASYKTGFBR1 | |
| SCHEMBL437390 | 0.83 | ATR (0.52) | ATRGSK3BDYRK1AIRAK4JAK2 | |
| SCHEMBL30633355 | 0.83 | ATR (0.46) | ATRGSK3BDYRK1ATGFBR1NAMPT | |
| SCHEMBL7909650 | 0.83 | ATR (0.46) | ATRGSK3BDYRK1ASYKTGFBR1 | |
| SCHEMBL29840658 | 0.83 | ATR (0.52) | ATRGSK3BDYRK1AIRAK4JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630115-A1 | THERAPEUTIC COMPOUNDS | Sanofi (FR) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121427-A1 | THERAPEUTIC COMPOUNDS | SANOFI (FR) | 2024-06-13 | — | — | WO | disclosed |