SCHEMBL30953498

SCHEMBL30953498

CC(C)(C)[Si](C)(C)OCc1ccnc(NC(=O)C(NC(=O)OCc2ccccc2)C2CCC(F)CC2)c1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ NR3C2 P08235 2/20 0.38
▸ ATM Q13315 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ MEN1 O00255 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ ANPEP P15144 1/20 0.35
▸ CTSK P43235 2/20 0.35
▸ CTSL P07711 2/20 0.35
▸ CTSS P25774 2/20 0.35
▸ MAPK13 O15264 1/20 0.35
▸ CTSB P07858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953242 0.93 NR3C2 (0.38) NR3C2ATMCYP1A2MEN1KMT2A
SCHEMBL30953283 0.87 NR3C2 (0.42) NR3C2ATMCYP1A2MEN1KMT2A
SCHEMBL30953303 0.87 NR3C2 (0.42) NR3C2ATMCYP1A2MEN1KMT2A
SCHEMBL30953421 0.82 ANPEP (0.40) NR3C2ANPEPCTSKCTSLCTSS
SCHEMBL30953276 0.81 AAK1 (0.44) NR3C2MAPK13
SCHEMBL30953457 0.81 ANPEP (0.39) NR3C2ANPEP
SCHEMBL30953268 0.80 NR3C2 (0.42) NR3C2ATMCYP1A2MEN1KMT2A
SCHEMBL30953293 0.79 AAK1 (0.41) NR3C2MAPK13
SCHEMBL30953507 0.75 ANPEP (0.40) NR3C2CYP1A2ANPEPCTSKCTSL
SCHEMBL21865153 0.73 ANPEP (0.52) ATMCYP1A2ANPEPCTSKCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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