Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 15/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | LTK | P29376 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1484798 | 0.86 | KDM4E (0.48) | KDM4EALDH1A1LMNAGAAADORA1 | |
| SCHEMBL30953632 | 0.83 | KDM4E (0.65) | KDM4EALDH1A1LMNAGAAADORA1 | |
| SCHEMBL30953825 | 0.80 | KDM4E (0.60) | KDM4EALDH1A1LMNAGAAADORA1 | |
| SCHEMBL30953739 | 0.80 | ADORA1 (0.61) | KDM4EALDH1A1LMNAGAAADORA1 | |
| SCHEMBL9206837 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1LMNAGAAADORA1 | |
| Iodide SCHEMBL4960911 | 0.78 | KDM4E (0.97) | KDM4EALDH1A1LMNAGAAADORA1 | |
| SCHEMBL15075787 | 0.77 | KDM4E (0.56) | KDM4EALDH1A1LMNAGAAADORA1 | |
| SCHEMBL30953618 | 0.74 | KDM4E (0.65) | KDM4EALDH1A1LMNAGAAADORA1 | |
| SCHEMBL30953684 | 0.74 | KDM4E (0.65) | KDM4EALDH1A1LMNAGAAADORA1 | |
| SCHEMBL15174702 | 0.74 | ADORA1 (0.63) | KDM4EALDH1A1ADORA1CHEK1DAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140431-A1 | COMPOUNDS COMPRISING HETEROARYL RINGS AND COMPOSITIONS AND METHODS THEREOF | IONGEN THERAPEUTICS CO., LTD. (CN) | 2024-07-04 | — | — | WO | disclosed |