SCHEMBL30953833

SCHEMBL30953833

Nc1nc2c(s1)CCc1ccccc1-2

nearest known ligand 0.97

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 5/20 0.97
CHEK1 O14757 1/20 0.73
DAPK3 O43293 1/20 0.73
LTK P29376 1/20 0.73
MAPK8 P45983 1/20 0.73
CSNK1A1 P48729 1/20 0.73
CDK8 P49336 1/20 0.73
LIMK1 P53667 1/20 0.73
CDK5 Q00535 1/20 0.73
DYRK1A Q13627 1/20 0.73
LRRK2 Q5S007 1/20 0.73
CLK4 Q9HAZ1 1/20 0.73
DYRK1B Q9Y463 1/20 0.73
KDM4E B2RXH2 4/20 0.58
ALDH1A1 P00352 4/20 0.58
MAPT P10636 2/20 0.58
MPI P34949 2/20 0.58
ATP4A P20648 1/20 0.58
ATP4B P51164 1/20 0.58
LMNA P02545 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1745165 1.00 ADORA1 (0.97) ADORA1CHEK1DAPK3LTKMAPK8
Iodide SCHEMBL4957487 0.98 ADORA1 (1.00) ADORA1CHEK1DAPK3LTKMAPK8
SCHEMBL30953858 0.90 ADORA1 (0.79) ADORA1CHEK1DAPK3LTKMAPK8
SCHEMBL4288204 0.90 ADORA1 (0.79) ADORA1CHEK1DAPK3LTKMAPK8
Iodide SCHEMBL3989105 0.89 ADORA1 (0.82) ADORA1CHEK1DAPK3LTKMAPK8
SCHEMBL31321386 0.84 CHEK1 (1.00) ADORA1CHEK1DAPK3LTKMAPK8
SCHEMBL4959991 0.84 CHEK1 (1.00) ADORA1CHEK1DAPK3LTKMAPK8
Bromide SCHEMBL9004168 0.83 CHEK1 (0.97) ADORA1CHEK1DAPK3LTKMAPK8
Iodide SCHEMBL4959469 0.83 ADORA1 (1.00) ADORA1CHEK1DAPK3LTKMAPK8
SCHEMBL10076399 0.79 ADORA1 (0.64) ADORA1CHEK1DAPK3LTKMAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024140431-A1 COMPOUNDS COMPRISING HETEROARYL RINGS AND COMPOSITIONS AND METHODS THEREOF IONGEN THERAPEUTICS CO., LTD. (CN) 2024-07-04 WO disclosed