Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27312555 | 1.00 | MAPK1 (0.33) | MAPK1DUTHRH3P2RX7PDE4A | |
| SCHEMBL30954493 | 0.83 | MAPK1 (0.31) | MAPK1P2RX7 | |
| SCHEMBL27312767 | 0.83 | MAPK1 (0.31) | MAPK1P2RX7 | |
| SCHEMBL27312844 | 0.83 | MAPK1 (0.31) | MAPK1P2RX7 | |
| SCHEMBL30954525 | 0.83 | MAPK1 (0.31) | MAPK1P2RX7 | |
| SCHEMBL27312556 | 0.81 | PDE4A (0.34) | HRH3P2RX7PDE4A | |
| SCHEMBL30954517 | 0.81 | PDE4A (0.34) | HRH3P2RX7PDE4A | |
| SCHEMBL27312687 | 0.73 | PDE4A (0.52) | PDE4A | |
| SCHEMBL27312845 | 0.68 | — | — | |
| SCHEMBL30954522 | 0.66 | SMYD2 (0.34) | PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118524-A1 | AZAINDOLE COMPOUNDS AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | CEREVEL THERAPEUTICS, LLC (US) | 2024-06-06 | — | — | WO | disclosed |