Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 7/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19337171 | 0.91 | NOTUM (0.58) | SLC18A3SIGMAR1NOTUMHDAC1HDAC6 | |
| SCHEMBL9917019 | 0.83 | NOTUM (0.60) | SLC18A3SIGMAR1NOTUMHDAC1HDAC6 | |
| SCHEMBL29350111 | 0.83 | SLC18A3 (0.57) | SLC18A3SIGMAR1NOTUMHDAC1HDAC6 | |
| SCHEMBL31573145 | 0.83 | NOTUM (0.60) | SLC18A3SIGMAR1NOTUMHDAC1HDAC6 | |
| SCHEMBL14685818 | 0.81 | SLC18A3 (0.56) | SLC18A3SIGMAR1NOTUMHDAC1HDAC6 | |
| SCHEMBL29948572 | 0.81 | SLC18A3 (0.56) | SLC18A3SIGMAR1NOTUMHDAC1HDAC6 | |
| SCHEMBL2883895 | 0.80 | SLC18A3 (0.61) | SLC18A3SIGMAR1NOTUMHDAC1HDAC6 | |
| SCHEMBL31707401 | 0.79 | SLC18A3 (0.50) | SLC18A3SIGMAR1NOTUMHDAC1HDAC6 | |
| SCHEMBL22003803 | 0.79 | SLC18A3 (0.50) | SLC18A3SIGMAR1NOTUMHDAC1HDAC6 | |
| SCHEMBL1587507 | 0.79 | SLC18A3 (0.50) | SLC18A3SIGMAR1NOTUMHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125488-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 浙江海正药业股份有限公司 | 2024-06-20 | — | — | WO | disclosed |