Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 4/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.35 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30298030 | 1.00 | CSF1R (0.38) | CSF1RSMOGRM1ELANELMNA | |
| SCHEMBL30297965 | 0.91 | GRM1 (0.38) | CSF1RSMOGRM1LMNAMAPT | |
| SCHEMBL30298068 | 0.89 | GRM1 (0.37) | SMOGRM1MAPT | |
| SCHEMBL30298037 | 0.85 | CSF1R (0.39) | CSF1RGRM1ELANELMNAMAPT | |
| SCHEMBL30297987 | 0.83 | CSF1R (0.41) | CSF1RSMOLMNAMAPTALDH1A1 | |
| SCHEMBL30954831 | 0.83 | CSF1R (0.41) | CSF1RSMOLMNAMAPTALDH1A1 | |
| SCHEMBL31157449 | 0.82 | KMT2A (0.44) | LMNAALDH1A1KMT2AKDM4EHTT | |
| SCHEMBL30297993 | 0.81 | ELANE (0.39) | CSF1RELANELMNAMAPTALDH1A1 | |
| SCHEMBL31157536 | 0.80 | EPHA2 (0.35) | SMOGRM1LMNAMAPTALDH1A1 | |
| SCHEMBL31157499 | 0.80 | GRM1 (0.42) | SMOGRM1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201914-A | 4-Oxo-1, 4-dihydroquinoline-3-carboxylic acid derivatives as PAPD5 and/or PAPD7 inhibitors | 雷多纳治疗公司 | 2024-06-14 | — | — | CN | disclosed |