Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20365013 | 0.86 | NOTUM (0.32) | MAP4K1PARP10PARP11NOTUM | |
| SCHEMBL23055381 | 0.74 | NOTUM (0.38) | PARP10PARP11NOTUM | |
| SCHEMBL18392953 | 0.72 | NOTUM (0.34) | MAP4K1PARP10PARP11NOTUM | |
| SCHEMBL30107339 | 0.71 | NOTUM (0.32) | MAP4K1PARP10PARP11NOTUM | |
| SCHEMBL21029685 | 0.69 | NOTUM (0.32) | PARP10PARP11NOTUM | |
| SCHEMBL15870167 | 0.68 | HTR2A (0.37) | MAP4K1PARP10PARP11NOTUM | |
| SCHEMBL25111467 | 0.68 | NOTUM (0.34) | MAP4K1NOTUM | |
| SCHEMBL14671492 | 0.68 | MAP4K1 (0.38) | MAP4K1NOTUM | |
| SCHEMBL19633371 | 0.68 | NOTUM (0.35) | MAP4K1PARP10PARP11NOTUM | |
| SCHEMBL30955180 | 0.66 | NOTUM (0.37) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638441-A1 | GLYCINE DERIVATIVES WITH P2X4 RECEPTOR-BLOCKING ACTIVITY AS DIAGNOSTICS AND FOR THE TREATMENT OF PAIN, INFLAMMATION, CANCER, AND OTHER P2X4 RECEPTOR-RELATED DISEASES | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024133499-A1 | GLYCINE DERIVATIVES WITH P2X4 RECEPTOR-BLOCKING ACTIVITY AS DIAGNOSTICS AND FOR THE TREATMENT OF PAIN, INFLAMMATION, CANCER, AND OTHER P2X4 RECEPTOR-RELATED DISEASES | RHEINISCHE-FRIEDRICH-WILHELMS-UNIVERSITÄT BONN (DE) | 2024-06-27 | — | — | WO | disclosed |