Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 3/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30955695 | 0.87 | FGFR4 (0.45) | FGFR4PIM1TTKPIM2FGFR1 | |
| SCHEMBL30955670 | 0.85 | FGFR4 (0.41) | FGFR4FGFR1FGFR2 | |
| SCHEMBL1522002 | 0.82 | FGFR4 (0.49) | FGFR4PIM1TTKPIM2FGFR1 | |
| SCHEMBL1521518 | 0.81 | FGFR4 (0.42) | FGFR4PIM1TTKPIM2FGFR1 | |
| SCHEMBL30955662 | 0.78 | ERN1 (0.40) | FGFR4 | |
| SCHEMBL30955653 | 0.77 | FGFR4 (0.50) | FGFR4PIM1TTKPIM2 | |
| SCHEMBL30955644 | 0.77 | FGFR4 (0.42) | FGFR4FGFR1FGFR2 | |
| SCHEMBL1521639 | 0.76 | FGFR4 (0.50) | FGFR4PIM1TTKPIM2FGFR1 | |
| SCHEMBL24170655 | 0.76 | FGFR4 (0.47) | FGFR4PIM1TTKPIM2 | |
| SCHEMBL6619641 | 0.74 | FGFR4 (0.45) | FGFR4PIM1TTKPIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131893-A1 | IRE1α SMALL MOLECULE INHIBITORS | SHANGHAI YI ZHONG XING BIOTECHNOLOGY CO., LTD. (CN) | 2024-06-27 | — | — | WO | disclosed |