Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 4/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.30 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30955759 | 1.00 | SMYD2 (0.43) | SMYD2CYP3A4HTTSMN1; SMN2IDO1 | |
| SCHEMBL30726327 | 1.00 | SMYD2 (0.43) | SMYD2CYP3A4HTTSMN1; SMN2IDO1 | |
| SCHEMBL31644559 | 0.93 | SMYD2 (0.41) | SMYD2CYP3A4HTTSMN1; SMN2IDO1 | |
| SCHEMBL599855 | 0.89 | SMYD2 (0.43) | SMYD2CYP3A4HTTSMN1; SMN2IDO1 | |
| SCHEMBL2017541 | 0.89 | SMYD2 (0.43) | SMYD2CYP3A4HTTSMN1; SMN2IDO1 | |
| SCHEMBL15822129 | 0.87 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2CHRM2 | |
| SCHEMBL27156635 | 0.87 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2CHRM2 | |
| SCHEMBL15822127 | 0.87 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2CHRM2 | |
| SCHEMBL31644626 | 0.85 | SMYD2 (0.40) | SMYD2CYP3A4HTTSMN1; SMN2IDO1 | |
| SCHEMBL31645002 | 0.85 | SMYD2 (0.40) | SMYD2CYP3A4HTTSMN1; SMN2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638454-A1 | SUBSTITUTED IMIDAZO-BASED COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK3 | Celgene Corporation (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137743-A1 | SUBSTITUTED IMIDAZO-BASED COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK3 | CELGENE CORPORATION (US) | 2024-06-27 | — | — | WO | disclosed |