Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.60 |
| ▸ | IGF1R | P08069 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29274174 | 1.00 | EGFR (0.60) | EGFRIGF1RKCNH2 | |
| SCHEMBL29375975 | 0.87 | EGFR (0.77) | EGFRIGF1RKCNH2 | |
| SCHEMBL29274175 | 0.87 | EGFR (0.77) | EGFRIGF1RKCNH2 | |
| SCHEMBL29375273 | 0.85 | EGFR (0.73) | EGFRIGF1RKCNH2 | |
| SCHEMBL29374836 | 0.82 | EGFR (0.69) | EGFRIGF1RKCNH2 | |
| SCHEMBL29372621 | 0.81 | EGFR (0.67) | EGFRIGF1RKCNH2 | |
| SCHEMBL29375690 | 0.81 | EGFR (0.67) | EGFRIGF1RKCNH2 | |
| SCHEMBL29375885 | 0.80 | EGFR (0.66) | EGFRIGF1RKCNH2 | |
| SCHEMBL29375296 | 0.78 | EGFR (0.71) | EGFRIGF1RKCNH2 | |
| SCHEMBL28383514 | 0.78 | EGFR (0.83) | EGFRIGF1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197203-B | Aniline pyrimidine compound, preparation method and application thereof | 上海医药工业研究院 | 2024-06-25 | — | — | CN | disclosed |