Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 5/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.41 |
| ▸ | PFKFB4 | Q16877 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25072476 | 1.00 | PLAU (0.47) | PLAUPTPN11PLATALPLPFKFB3 | |
| SCHEMBL30278495 | 1.00 | PLAU (0.47) | PLAUPTPN11PLATALPLPFKFB3 | |
| SCHEMBL30278475 | 0.89 | PTPN11 (0.46) | PTPN11ALPLPFKFB3MEN1KMT2A | |
| SCHEMBL25072449 | 0.89 | PTPN11 (0.46) | PTPN11ALPLPFKFB3MEN1KMT2A | |
| SCHEMBL25073129 | 0.85 | PTPN11 (0.42) | PTPN11MEN1KMT2AMAPTLMNA | |
| SCHEMBL25072742 | 0.82 | SMN1; SMN2 (0.48) | ALPLMEN1KMT2AMAPTLMNA | |
| SCHEMBL25072756 | 0.80 | NPY5R (0.46) | PLAUALPLMEN1KMT2AMAPT | |
| SCHEMBL25072408 | 0.80 | PTPN11 (0.51) | PTPN11MEN1KMT2APTPN1MAPT | |
| SCHEMBL25072478 | 0.79 | PTPN11 (0.44) | PLAUPTPN11MEN1KMT2ACYP19A1 | |
| SCHEMBL25073333 | 0.79 | KDM4E (0.47) | PTPN11KMT2AMAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103038-A | 17 Beta-hydroxysteroid dehydrogenase 13 inhibitors and methods of use thereof | 英安塔制药有限公司 | 2024-05-28 | — | — | CN | disclosed |