Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 4/20 | 0.59 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.59 |
| ▸ | ITGAL | P20701 | 4/20 | 0.59 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27429060 | 1.00 | ITGB2 (0.59) | ITGB2ICAM1ITGALSOS2POLB | |
| SCHEMBL21392024 | 1.00 | ITGB2 (0.59) | ITGB2ICAM1ITGALSOS2POLB | |
| SCHEMBL24042700 | 0.90 | SOS2 (0.57) | ITGB2ICAM1ITGALSOS2POLB | |
| SCHEMBL24975589 | 0.90 | SOS2 (0.57) | ITGB2ICAM1ITGALSOS2POLB | |
| SCHEMBL14950880 | 0.90 | SOS2 (0.57) | ITGB2ICAM1ITGALSOS2POLB | |
| SCHEMBL27431642 | 0.88 | ITGB2 (0.58) | ITGB2ICAM1ITGALSOS2POLB | |
| SCHEMBL28516953 | 0.87 | ITGB2 (0.63) | ITGB2ICAM1ITGALSOS2POLB | |
| SCHEMBL28516957 | 0.87 | ITGB2 (0.63) | ITGB2ICAM1ITGALSOS2POLB | |
| SCHEMBL22989842 | 0.86 | SOS2 (0.51) | ITGB2ICAM1ITGALSOS2POLB | |
| SCHEMBL837759 | 0.86 | ITGB2 (0.53) | ITGB2ICAM1ITGALHTR2ATNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184642-A | Aromatic ring system heterocycle compound, and pharmaceutical composition and application thereof | 中国药科大学 | 2024-06-14 | — | — | CN | disclosed |