SCHEMBL3095599

SCHEMBL3095599

CCCCCCCCCCC(Br)CCCCCCC

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.52
PPARD Q03181 1/20 0.52
ZDHHC20 Q5W0Z9 1/20 0.52
ZDHHC2 Q9UIJ5 1/20 0.52
TSHR P16473 1/20 0.50
THRB P10828 1/20 0.50
LMNA P02545 1/20 0.48
DNM1 Q05193 2/20 0.48
ZDHHC7 Q9NXF8 1/20 0.46
OPRM1 P35372 1/20 0.46
GPR84 Q9NQS5 3/20 0.42
FDPS P14324 3/20 0.42
SPHK1 Q9NYA1 1/20 0.42
FFAR1 O14842 1/20 0.42
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15687768 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL9544301 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL12214087 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL8878248 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL9318142 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL340114 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL5902659 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL7092874 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL12964460 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL9544366 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748358-B2 Lubricating oil additive, lubricating oil composition containing the same, various low-friction sliding members, rolling bearing, and sliding bearing IDEMITSU KOSAN CO., LTD. (JP) 2014-06-10 US disclosed
US-20100234254-A1 LUBRICATING OIL ADDITIVE, LUBRICATING OIL COMPOSITION CONTAINING THE SAME, VARIOUS LOW-FRICTION SLIDING MEMBERS, ROLLING BEARING, AND SLIDING BEARING IDEMITSU KOSAN CO., LTD. (JP) 2010-09-16 US disclosed
EP-2011853-A1 LUBRICATING OIL ADDITIVE, LUBRICATING OIL COMPOSITION CONTAINING THE SAME, VARIOUS LOW-FRICTION SLIDING MEMBERS, ROLLING BEARING, AND SLIDING BEARING Idemitsu Kosan Co., Ltd. (JP) 2009-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234254-A1 LUBRICATING OIL ADDITIVE, LUBRICATING OIL COMPOSITION CONTAINING THE SAME, VARIOUS LOW-FRICTION SLIDING MEMBERS, ROLLING BEARING, AND SLIDING BEARING TYK2, TEC, AXL LCK 196/4885PPARD 61/4885ZDHHC20 1725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.