Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30787481 | 0.91 | MAOB (0.75) | MAOBMAOAMAPTHPGDALDH1A1 | |
| SCHEMBL30956083 | 0.85 | MAOB (0.80) | MAOBMAOAMAPTCYP1A2CYP3A4 | |
| SCHEMBL30661291 | 0.76 | MAOB (0.53) | MAOBMAPTHPGDHTTKDM4E | |
| SCHEMBL19198638 | 0.75 | KDM4C (0.57) | MAOBMAOAALDH1A1KDM4ECA2 | |
| SCHEMBL28902170 | 0.74 | MAOB (1.00) | MAOBMAOAMAPTCA2CA12 | |
| SCHEMBL30167102 | 0.74 | MAOB (1.00) | MAOBMAOAMAPTCA2CA12 | |
| SCHEMBL30956075 | 0.74 | MAOB (0.52) | MAOBMAOAMAPTHTTALDH1A1 | |
| SCHEMBL30956090 | 0.73 | MAOB (0.59) | MAOBMAOAMAPTCYP1A2ALDH1A1 | |
| SCHEMBL30167103 | 0.73 | MAOB (0.79) | MAOBMAOACA2CA12CA9 | |
| SCHEMBL28902190 | 0.73 | MAOB (0.79) | MAOBMAOACA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005692-A | Preparation of benzofuran derivative by initiating free radical reaction by superelectron donor with heteroatom as center and application | 贵州大学 | 2024-05-10 | — | — | CN | disclosed |