Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 17/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.55 |
| ▸ | CDK2 | P24941 | 5/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | CDK8 | P49336 | 1/20 | 0.55 |
| ▸ | CDK7 | P50613 | 1/20 | 0.55 |
| ▸ | CDK9 | P50750 | 1/20 | 0.55 |
| ▸ | FLT4 | P35916 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30956491 | 0.92 | IGF1R (0.47) | IGF1RKCNH2CDK2CDK1CDK8 | |
| SCHEMBL28606153 | 0.91 | IGF1R (0.49) | IGF1RKCNH2CDK2CDK1CDK8 | |
| SCHEMBL30956585 | 0.87 | CDK2 (0.55) | IGF1RKCNH2CDK2CDK1CDK8 | |
| SCHEMBL24853395 | 0.87 | IGF1R (0.52) | IGF1RKCNH2CDK2CDK1CDK8 | |
| SCHEMBL29942021 | 0.87 | IGF1R (0.52) | IGF1RKCNH2CDK2CDK1CDK8 | |
| SCHEMBL30956411 | 0.87 | IGF1R (0.57) | IGF1RKCNH2CDK2CDK1CDK8 | |
| SCHEMBL30956562 | 0.87 | FLT4 (0.57) | IGF1RKCNH2CDK2CDK1CDK8 | |
| SCHEMBL30956431 | 0.83 | FLT4 (0.57) | IGF1RKCNH2CDK2CDK1CDK8 | |
| SCHEMBL24853406 | 0.80 | IGF1R (0.47) | IGF1RKCNH2CDK2CDK1CDK8 | |
| SCHEMBL30956618 | 0.80 | JAK3 (0.53) | IGF1RKCNH2CDK2CDK1CDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119118999-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-118955477-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118903141-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-118903142-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-113227074-B | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-118388457-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-118290403-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-07-05 | — | — | CN | disclosed |