Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 11/20 | 0.81 |
| ▸ | EZH1 | Q92800 | 12/20 | 0.78 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.73 |
| ▸ | EED | O75530 | 1/20 | 0.73 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.73 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.73 |
| ▸ | RBBP7 | Q16576 | 1/20 | 0.73 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.73 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20992055 | 1.00 | EZH2 (0.81) | EZH2EZH1PRMT3EEDRBBP4 | |
| SCHEMBL2592678 | 0.94 | EZH2 (0.81) | EZH2EZH1PRMT3EEDRBBP4 | |
| SCHEMBL23863738 | 0.94 | EZH2 (0.72) | EZH2EZH1PRMT3EEDRBBP4 | |
| SCHEMBL2594803 | 0.93 | EZH1 (0.82) | EZH2EZH1PRMT3EEDRBBP4 | |
| SCHEMBL30956748 | 0.92 | EZH2 (0.80) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL29261030 | 0.92 | EZH2 (0.80) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL16767552 | 0.90 | EZH1 (0.92) | EZH2EZH1PRMT3EEDRBBP4 | |
| SCHEMBL29351394 | 0.90 | EZH1 (0.92) | EZH2EZH1PRMT3EEDRBBP4 | |
| SCHEMBL14917586 | 0.90 | EZH2 (0.66) | EZH2EZH1PRMT3EEDRBBP4 | |
| SCHEMBL2592693 | 0.90 | EZH1 (0.68) | EZH2EZH1PRMT3EEDRBBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201612-A | Compositions and methods for combination therapy for the treatment of lymphomas | 上海睿跃生物科技有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118201612-A | Compositions and methods for combination therapy for the treatment of lymphomas | 上海睿跃生物科技有限公司 | 2024-06-14 | — | — | CN | disclosed |