Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 10/20 | 1.00 |
| ▸ | PDGFRB | P09619 | 5/20 | 1.00 |
| ▸ | KIT | P10721 | 5/20 | 1.00 |
| ▸ | PDGFRA | P16234 | 5/20 | 1.00 |
| ▸ | FLT3 | P36888 | 5/20 | 1.00 |
| ▸ | RAF1 | P04049 | 10/20 | 0.58 |
| ▸ | BRAF | P15056 | 10/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sotuletinib SCHEMBL2677068 | 1.00 | CSF1R (1.00) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| Sotuletinib SCHEMBL2677120 | 1.00 | CSF1R (1.00) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| Sotuletinib SCHEMBL29368661 | 1.00 | CSF1R (1.00) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| Sotuletinib SCHEMBL29368442 | 1.00 | CSF1R (1.00) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| Sotuletinib SCHEMBL2676695 | 1.00 | CSF1R (1.00) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| Sotuletinib SCHEMBL2676088 | 1.00 | CSF1R (1.00) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| Sotuletinib SCHEMBL23259540 | 1.00 | CSF1R (1.00) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| Sotuletinib SCHEMBL19415435 | 1.00 | CSF1R (1.00) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| Sotuletinib SCHEMBL13824540 | 1.00 | CSF1R (1.00) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| Sotuletinib SCHEMBL4550965 | 1.00 | CSF1R (1.00) | CSF1RPDGFRBKITPDGFRAFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4602042-A1 | SALT FORMS OF IRAK4 DEGRADERS | Kymera Therapeutics, Inc. (US) | 2025-08-20 | — | — | EP | disclosed |
| WO-2024081893-A1 | SALT FORMS OF IRAK4 DEGRADERS | KYMERA THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |