SCHEMBL30956931

SCHEMBL30956931

Cn1cnnc1-c1ccc(C#N)cc1-c1cc(NC2(CC#N)CC2)nc(N2Cc3c(cc(CN4CCC5(CC5)C4)cc3C(F)(F)F)C2=O)c1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27292816 1.00 CBLB (0.55) CBLB
SCHEMBL27296121 0.98 CBLB (0.56) CBLB
SCHEMBL27323480 0.94 CBLB (0.54) CBLB
SCHEMBL27294820 0.93 CBLB (0.52) CBLB
SCHEMBL27296567 0.93 CBLB (0.57) CBLB
SCHEMBL27296565 0.93 CBLB (0.57) CBLB
SCHEMBL27298338 0.92 CBLB (0.54) CBLB
SCHEMBL27298336 0.92 CBLB (0.55) CBLB
SCHEMBL27297159 0.92 CBLB (0.52) CBLB
SCHEMBL27299555 0.92 CBLB (0.57) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4602028-A1 CBL-B MODULATORS AND USES THEREOF Nimbus Clio, Inc. (US) 2025-08-20 — — EP disclosed
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 — — WO disclosed
Send feedback