SCHEMBL30956957

SCHEMBL30956957

Cn1cnnc1-c1ccc(C#N)cc1-c1cc(NCCC2CC2)nc(N2Cc3c(cc(CN4CCC5(CC5)C4)cc3C(F)(F)F)C2=O)c1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27290747 1.00 CBLB (0.57) CBLB
SCHEMBL27294882 0.98 CBLB (0.57) CBLB
SCHEMBL27298330 0.98 CBLB (0.57) CBLB
SCHEMBL27298225 0.98 CBLB (0.59) CBLB
SCHEMBL27298229 0.97 CBLB (0.57) CBLB
SCHEMBL27296946 0.97 CBLB (0.58) CBLB
SCHEMBL27298226 0.96 CBLB (0.55) CBLB
SCHEMBL27298232 0.96 CBLB (0.59) CBLB
SCHEMBL30956925 0.95 CBLB (0.57) CBLB
SCHEMBL27308610 0.95 CBLB (0.57) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4602028-A1 CBL-B MODULATORS AND USES THEREOF Nimbus Clio, Inc. (US) 2025-08-20 — — EP disclosed
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 — — WO disclosed
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