SCHEMBL30957375

SCHEMBL30957375

CC(C)(c1ccccc1)N(CCCCCN(C(=O)O)C(C)(C)c1ccccc1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.43
CYP2C19 P33261 2/20 0.43
MEN1 O00255 2/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HIF1A Q16665 1/20 0.43
OPRM1 P35372 2/20 0.42
DRD3 P35462 2/20 0.42
DRD4 P21917 1/20 0.42
MAPT P10636 1/20 0.40
HDAC3 O15379 2/20 0.39
HDAC1 Q13547 2/20 0.39
HDAC2 Q92769 2/20 0.39
HDAC6 Q9UBN7 2/20 0.39
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 1/20 0.39
RIPK1 Q13546 2/20 0.39
DRD2 P14416 1/20 0.39
SIGMAR1 Q99720 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25262749 0.86 MAPT (0.40) KMT2ACYP2C19MEN1CYP3A4CYP2C9
SCHEMBL235905 0.78 NPC1 (0.47) OPRM1DRD3ALDH1A1DRD2SIGMAR1
SCHEMBL235949 0.78 NPC1 (0.47) OPRM1DRD3ALDH1A1DRD2SIGMAR1
SCHEMBL233200 0.78 NPC1 (0.47) OPRM1DRD3ALDH1A1DRD2SIGMAR1
SCHEMBL235953 0.78 NPC1 (0.47) OPRM1DRD3ALDH1A1DRD2SIGMAR1
SCHEMBL235012 0.78 NPC1 (0.47) OPRM1DRD3ALDH1A1DRD2SIGMAR1
SCHEMBL14801949 0.76 CYP2C9 (0.45) KMT2ACYP2C19MEN1CYP3A4CYP2C9
SCHEMBL3321783 0.73 HDAC3 (0.56) KMT2AMEN1HDAC3HDAC1HDAC2
SCHEMBL28525204 0.71 KMT2A (0.49) KMT2AMEN1OPRM1DRD3DRD4
SCHEMBL27262221 0.71 MAPT (0.47) KMT2ACYP2C19CYP3A4HIF1AOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118215651-A Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition 旭化成株式会社 2024-06-18 CN disclosed