Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.44 |
| ▸ | CCNK | O75909 | 3/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.44 |
| ▸ | CDK2 | P24941 | 3/20 | 0.44 |
| ▸ | CDK9 | P50750 | 3/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.44 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 1/20 | 0.40 |
| ▸ | ATP4B | P51164 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 2/20 | 0.40 |
| ▸ | CCNH | P51946 | 2/20 | 0.40 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24900366 | 1.00 | AR (0.47) | ARCCNT1CCNKCCNE1CDK2 | |
| SCHEMBL30957550 | 0.90 | DYRK1A (0.53) | ARRPS6KA5DYRK1ANFATC1GSK3B | |
| SCHEMBL24900358 | 0.90 | DYRK1A (0.53) | ARRPS6KA5DYRK1ANFATC1GSK3B | |
| SCHEMBL30957556 | 0.87 | CCNT1 (0.43) | ARCCNT1CCNKCCNE1CDK2 | |
| SCHEMBL24900454 | 0.87 | CCNT1 (0.43) | ARCCNT1CCNKCCNE1CDK2 | |
| SCHEMBL24900582 | 0.85 | RPS6KA5 (0.60) | ARCCNT1CCNKCCNE1CDK2 | |
| SCHEMBL30957639 | 0.82 | CCNT1 (0.55) | ARCCNT1CCNKCCNE1CDK2 | |
| SCHEMBL24900677 | 0.82 | CCNT1 (0.55) | ARCCNT1CCNKCCNE1CDK2 | |
| SCHEMBL24900727 | 0.81 | RPS6KA5 (0.56) | ARCCNT1CCNKCCNE1CDK2 | |
| SCHEMBL17542563 | 0.81 | CDK7 (0.54) | RPS6KA5CDK7CCNHMNAT1CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159533-A | Heterocyclic compounds and their use | 艾森医药有限公司 | 2024-06-07 | — | — | CN | disclosed |