Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.63 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29243200 | 1.00 | ESR1 (0.63) | ESR1AGTR2ESR2 | |
| SCHEMBL29243199 | 1.00 | ESR1 (0.63) | ESR1AGTR2ESR2 | |
| SCHEMBL29243198 | 0.94 | ESR1 (0.64) | ESR1AGTR2 | |
| SCHEMBL20165083 | 0.88 | ESR1 (0.80) | ESR1 | |
| SCHEMBL20165080 | 0.88 | ESR1 (0.80) | ESR1 | |
| SCHEMBL29243195 | 0.88 | ESR1 (0.83) | ESR1 | |
| SCHEMBL23335761 | 0.86 | ESR1 (0.61) | ESR1AGTR2 | |
| SCHEMBL19131916 | 0.86 | ESR1 (0.63) | ESR1AGTR2 | |
| SCHEMBL31739214 | 0.86 | ESR1 (0.63) | ESR1AGTR2 | |
| SCHEMBL24022240 | 0.86 | ESR1 (0.63) | ESR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255703-A | Preparation method of estrogen receptor degradation agent | 南京医科大学 | 2024-06-28 | — | — | CN | disclosed |