Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 13/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6228072 | 0.88 | GRIN1 (0.51) | EPHX2HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL23241867 | 0.86 | EPHX2 (0.55) | EPHX2HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL6229217 | 0.86 | EPHX2 (0.46) | EPHX2HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL19420470 | 0.83 | EPHX2 (0.53) | EPHX2HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL19602976 | 0.83 | EPHX2 (0.53) | EPHX2HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL24586188 | 0.82 | EPHX2 (0.48) | EPHX2 | |
| SCHEMBL21466609 | 0.82 | EPHX2 (0.52) | EPHX2HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL23246133 | 0.81 | EPHX2 (0.67) | EPHX2HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL21461244 | 0.81 | EPHX2 (0.62) | EPHX2HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL23246134 | 0.81 | EPHX2 (0.67) | EPHX2HDAC1HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271201-A | With NMDA receptor-Ca2+Heterodiad compound with channel as target point, and preparation method and application thereof | 合肥工业大学 | 2024-07-02 | — | — | CN | disclosed |