Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 13/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 4/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.35 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30958844 | 0.89 | SCN10A (0.41) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL30958773 | 0.85 | SCN10A (0.44) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24906394 | 0.84 | SCN10A (0.44) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24757296 | 0.84 | SCN10A (0.44) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24757299 | 0.84 | SCN10A (0.44) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24757786 | 0.84 | ANO1 (0.44) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24757797 | 0.83 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24906227 | 0.83 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24906235 | 0.83 | SCN10A (0.40) | SCN10AANO1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL24759022 | 0.83 | SCN10A (0.43) | SCN10AANO1SLC2A1SLC2A3SLC2A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4385979-A1 | MULTICYCLIC INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | disclosed |