⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1177847 | 0.97 | — | — | |
| Pyridine SCHEMBL17653500 | 0.80 | TSHR (0.36) | — | |
| SCHEMBL2285647 | 0.77 | — | — | |
| SCHEMBL2185400 | 0.73 | — | — | |
| SCHEMBL6524377 | 0.69 | EPHX1 (0.42) | — | |
| SCHEMBL29053973 | 0.69 | — | — | |
| SCHEMBL15765723 | 0.69 | — | — | |
| SCHEMBL25400461 | 0.65 | — | — | |
| SCHEMBL11499849 | 0.65 | — | — | |
| SCHEMBL10409161 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108264639-B | Temperature and pH dual-responsiveness cinnamic acid-polyasparagine conjugate and water phase crosslinking method thereof | 湖北工业大学 | 2020-08-07 | — | — | CN | claimed |
| CN-110841071-A | Poly (β -amino ester) drug delivery system loaded with bioactive substances and preparation method thereof | 南通大学 | 2020-02-28 | — | — | CN | claimed |
| CN-116999570-A | Tumor-targeted polypeptide drug conjugate and application thereof | 兰州大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-110841071-B | Poly (beta-amino ester) drug delivery system loaded with bioactive substances and preparation method thereof | 南通大学 | 2023-03-31 | — | — | CN | disclosed |
| EP-4048657-A1 | PROCESSES FOR MAKING TETRAZOLINONE COMPOUNDS | BASF SE (DE) | 2022-08-31 | — | — | EP | disclosed |
| US-11254966-B2 | Cysteine labelling | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2022-02-22 | — | — | US | disclosed |
| WO-2021078698-A1 | PROCESSES FOR MAKING TETRAZOLINONE COMPOUNDS | BASF SE (DE) | 2021-04-29 | — | — | WO | disclosed |
| EP-3784659-A1 | PROCESS FOR THE PREPARATION OF 1-(2-METHOXYMETHYL-3-METHYLPHENYL)4H-TETRAZOLIN-5-ONE | BASF SE (DE) | 2021-03-03 | — | — | EP | disclosed |
| US-10829799-B2 | Cysteine labelling | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2020-11-10 | — | — | US | disclosed |
| CN-108264639-B | Temperature and pH dual-responsiveness cinnamic acid-polyasparagine conjugate and water phase crosslinking method thereof | 湖北工业大学 | 2020-08-07 | — | — | CN | disclosed |
| US-20200172954-A1 | Cysteine Labelling | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2020-06-04 | — | — | US | disclosed |
| WO-2016051174-A1 | CYSTEINE LABELLING | UNIVERSITY OF DUNDEE (GB) | 2016-04-07 | — | — | WO | disclosed |
| EP-2013187-B1 | DIARYLTHIOHYDANTOIN COMPOUNDS | UNIV CALIFORNIA (US) | 2014-10-29 | — | — | EP | disclosed |
| US-20130281646-A1 | MULTIFUNCTIONAL LINKERS | KORZEKWA KENNETH (US) | 2013-10-24 | — | — | US | disclosed |
| WO-2013001451-A1 | VECTOR FOR THE RELEASE OF AN ACTIVE AGENT WHICH IS PHOTOCLEAVABLE BY IRRADIATION IN THE VISIBLE | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2013-01-03 | — | — | WO | disclosed |
| US-20100240773-A1 | MULTIFUNCTIONAL LINKERS | KORZEKWA KENNETH | 2010-09-23 | — | — | US | disclosed |
| US-20090069561-A1 | CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-03-12 | — | — | US | disclosed |
| EP-1765910-A2 | CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS | The Scripps Research Institute (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005046-A9 | CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS | SCRIPPS RESEARCH INST (US) | 2006-03-09 | — | — | WO | disclosed |
| WO-2006005046-A2 | CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-01-12 | — | — | WO | disclosed |