Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 7/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24837580 | 0.81 | TSHR (0.47) | TSHRTACR1SLC6A4 | |
| SCHEMBL25212600 | 0.81 | TSHR (0.47) | TSHRTACR1SLC6A4 | |
| SCHEMBL31450118 | 0.81 | TSHR (0.47) | TSHRTACR1SLC6A4 | |
| SCHEMBL25210438 | 0.81 | TSHR (0.47) | TSHRTACR1SLC6A4 | |
| SCHEMBL29345920 | 0.80 | TSHR (0.45) | TSHRTACR1MMP2MMP3MMP9 | |
| SCHEMBL27153702 | 0.79 | TSHR (0.36) | TSHRTACR1L3MBTL1SLC6A4IDO1 | |
| SCHEMBL27153701 | 0.79 | TSHR (0.36) | TSHRTACR1L3MBTL1SLC6A4IDO1 | |
| SCHEMBL25240765 | 0.79 | TSHR (0.41) | TSHRTACR1SLC6A4 | |
| SCHEMBL31387728 | 0.79 | TSHR (0.41) | TSHRTACR1SLC6A4IDO1 | |
| SCHEMBL25240763 | 0.79 | TSHR (0.41) | TSHRTACR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615847-A1 | SMALL MOLECULE INHIBITORS OF KRAS PROTEINS | Merck Sharp & Dohme LLC (US) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024103010-A1 | SMALL MOLECULE INHIBITORS OF KRAS PROTEINS | MERCK SHARP & DOHME LLC (US) | 2024-05-16 | — | — | WO | disclosed |