Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25307042 | 1.00 | KRAS (0.40) | KRAS | |
| SCHEMBL31441816 | 0.89 | KRAS (0.40) | KRAS | |
| SCHEMBL30959903 | 0.89 | KRAS (0.40) | KRAS | |
| SCHEMBL25263610 | 0.89 | KRAS (0.40) | KRAS | |
| SCHEMBL31670180 | 0.89 | KRAS (0.35) | KRAS | |
| SCHEMBL26709683 | 0.89 | JAK1 (0.31) | KRAS | |
| SCHEMBL31341506 | 0.89 | KRAS (0.46) | KRAS | |
| SCHEMBL26119833 | 0.89 | KRAS (0.46) | KRAS | |
| SCHEMBL25309618 | 0.88 | KRAS (0.35) | KRAS | |
| SCHEMBL30148998 | 0.88 | KRAS (0.35) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141570-A9 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF KRAS | ARVINAS OPERATIONS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |