Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.39 |
| ▸ | WEE1 | P30291 | 2/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.35 |
| ▸ | JAK2 | O60674 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962668 | 0.88 | WEE1 (0.41) | EHMT2ALKWEE1TBK1JAK2 | |
| SCHEMBL30962917 | 0.88 | WEE1 (0.40) | EHMT2ALKWEE1TBK1JAK2 | |
| SCHEMBL30962858 | 0.88 | EHMT2 (0.37) | EHMT2ALKWEE1TBK1JAK2 | |
| SCHEMBL30962797 | 0.87 | WEE1 (0.47) | EHMT2ALKWEE1TBK1JAK2 | |
| SCHEMBL30962777 | 0.86 | WEE1 (0.46) | EHMT2ALKWEE1TBK1JAK2 | |
| SCHEMBL30962727 | 0.86 | ALK (0.45) | EHMT2ALKWEE1BRD4KCNH2 | |
| SCHEMBL30962694 | 0.85 | WEE1 (0.44) | EHMT2ALKWEE1TBK1JAK2 | |
| SCHEMBL30962572 | 0.85 | WEE1 (0.41) | EHMT2ALKWEE1TBK1JAK2 | |
| SCHEMBL30962810 | 0.84 | WEE1 (0.44) | EHMT2ALKWEE1JAK2 | |
| SCHEMBL30962824 | 0.83 | WEE1 (0.42) | EHMT2ALKWEE1TBK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |