Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 1/20 | 0.47 |
| ▸ | SIK1 | P57059 | 2/20 | 0.43 |
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.43 |
| ▸ | SIK3 | Q9Y2K2 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 9/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
| ▸ | HCK | P08631 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962904 | 0.94 | WEE1 (0.47) | WEE1SIK1SIK2SIK3SRC | |
| SCHEMBL27313752 | 0.94 | WEE1 (0.47) | WEE1SIK1SIK2SIK3SRC | |
| SCHEMBL30962897 | 0.93 | SIK1 (0.47) | WEE1SIK1SIK2SIK3SRC | |
| SCHEMBL27313416 | 0.92 | WEE1 (0.54) | WEE1SIK1SIK2SIK3SRC | |
| SCHEMBL30962937 | 0.91 | PTK2 (0.42) | WEE1SIK1SIK2SIK3SRC | |
| SCHEMBL27313419 | 0.90 | SRC (0.53) | WEE1SIK1SIK2SIK3SRC | |
| SCHEMBL30962699 | 0.90 | SRC (0.53) | WEE1SIK1SIK2SIK3SRC | |
| SCHEMBL30962688 | 0.89 | SIK1 (0.48) | WEE1SIK1SIK2SIK3SRC | |
| SCHEMBL30962737 | 0.89 | WEE1 (0.48) | WEE1SIK1SIK2SIK3SRC | |
| SCHEMBL30962868 | 0.89 | WEE1 (0.51) | WEE1SIK1SIK2SIK3SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |