Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 4/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.37 |
| ▸ | MERTK | Q12866 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | NPM1 | P06748 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | ROS1 | P08922 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | FGR | P09769 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962590 | 0.96 | UTS2R (0.38) | HSP90AA1HSP90AB1EGFRERBB2ALK | |
| SCHEMBL30962652 | 0.91 | EGFR (0.42) | EGFRERBB2ALKTYRO3MERTK | |
| Formic Acid SCHEMBL30962939 | 0.88 | EGFR (0.40) | EGFRERBB2ALKTYRO3MERTK | |
| SCHEMBL30962572 | 0.88 | WEE1 (0.41) | ALKJAK2RETROS1FLT3 | |
| SCHEMBL30962825 | 0.87 | EGFR (0.40) | EGFRERBB2ALKFGFR1KDR | |
| SCHEMBL30962809 | 0.83 | EHMT2 (0.37) | ALKJAK2EHMT2 | |
| SCHEMBL30962668 | 0.82 | WEE1 (0.41) | ALKJAK2RETROS1SRC | |
| SCHEMBL30962775 | 0.82 | ALK (0.42) | ALKJAK2CSF1RCAMK2DEHMT2 | |
| SCHEMBL30962965 | 0.81 | JAK3 (0.42) | EGFRRETSRCKDRSYK | |
| SCHEMBL30962846 | 0.80 | PTK2 (0.41) | EGFRALKCSF1RRETFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |