Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIK1 | P57059 | 2/20 | 0.50 |
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.50 |
| ▸ | SIK3 | Q9Y2K2 | 2/20 | 0.50 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 3/20 | 0.46 |
| ▸ | JAK3 | P52333 | 2/20 | 0.45 |
| ▸ | WEE1 | P30291 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | TEK | Q02763 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | TTK | P33981 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 7/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27313548 | 1.00 | SIK1 (0.50) | SIK1SIK2SIK3MAP4K1LCK | |
| SCHEMBL30962766 | 0.93 | SIK1 (0.54) | SIK1SIK2SIK3MAP4K1LCK | |
| SCHEMBL27313554 | 0.93 | WEE1 (0.51) | SIK1SIK2SIK3MAP4K1LCK | |
| SCHEMBL30962787 | 0.93 | WEE1 (0.51) | SIK1SIK2SIK3MAP4K1LCK | |
| SCHEMBL27313423 | 0.91 | LCK (0.51) | SIK1SIK2SIK3MAP4K1LCK | |
| SCHEMBL30962770 | 0.91 | LCK (0.51) | SIK1SIK2SIK3MAP4K1LCK | |
| SCHEMBL30962584 | 0.91 | SIK1 (0.44) | SIK1SIK2SIK3MAP4K1LCK | |
| SCHEMBL27313755 | 0.91 | SIK1 (0.44) | SIK1SIK2SIK3MAP4K1LCK | |
| SCHEMBL30962699 | 0.91 | SRC (0.53) | SIK1SIK2SIK3LCKJAK3 | |
| SCHEMBL27313419 | 0.91 | SRC (0.53) | SIK1SIK2SIK3LCKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |