Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.58 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.58 |
| ▸ | EP300 | Q09472 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 7/20 | 0.53 |
| ▸ | NPY4R | P50391 | 7/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.53 |
| ▸ | NPY1R | P25929 | 5/20 | 0.53 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.53 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.53 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.52 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32676360 | 0.96 | EP300 (0.59) | MAPK8MAPK9MAPK10EP300HIF1A | |
| SCHEMBL30712780 | 0.95 | NPY2R (0.58) | MAPK8MAPK9MAPK10EP300HIF1A | |
| SCHEMBL30712788 | 0.92 | EP300 (0.56) | MAPK8MAPK9MAPK10EP300HIF1A | |
| SCHEMBL30581208 | 0.88 | NPY2R (0.59) | MAPK8MAPK9MAPK10EP300HIF1A | |
| SCHEMBL31556380 | 0.87 | MAPK8 (0.55) | MAPK8MAPK9MAPK10EP300HIF1A | |
| SCHEMBL30525422 | 0.86 | EPHA2 (0.57) | EP300HIF1ANPY2RNPY4RNPY5R | |
| SCHEMBL30883213 | 0.85 | NMUR2 (0.64) | EP300HIF1ANPY2RNPY4RNPY5R | |
| SCHEMBL30788350 | 0.85 | NMUR2 (0.58) | NMUR2NMUR1EPHA2CXCR4 | |
| SCHEMBL31651397 | 0.85 | NPY2R (0.71) | MAPK8MAPK9MAPK10NPY2RNPY4R | |
| SCHEMBL30512535 | 0.85 | NMUR2 (0.63) | MAPK8MAPK9MAPK10NPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605008-A1 | ALPHA-V BETA-6 INTEGRIN LIGANDS FOR EXTRAHEPATIC DELIVERY | Alnylam Pharmaceuticals, Inc. (US) | 2025-08-27 | — | — | EP | disclosed |
| WO-2024129931-A1 | ALPHA-V BETA-6(ανβ6) INTEGRIN LIGANDS FOR EXTRAHEPATIC DELIVERY | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |