Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.35 |
| ▸ | CBLB | Q13191 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24819809 | 0.87 | CETP (0.38) | CETPCBLBMAPTSMN1; SMN2KDM4E | |
| SCHEMBL30153136 | 0.87 | CETP (0.38) | CETPCBLBMAPTSMN1; SMN2KDM4E | |
| SCHEMBL24819026 | 0.83 | KDM4C (0.37) | CETPSMN1; SMN2ALDH1A1 | |
| SCHEMBL30153007 | 0.81 | CBLB (0.36) | CETPCBLBMAP3K5 | |
| SCHEMBL24821927 | 0.81 | CBLB (0.36) | CETPCBLBMAP3K5 | |
| SCHEMBL30792010 | 0.81 | CBLB (0.36) | CETPCBLBMAP3K5 | |
| SCHEMBL30153218 | 0.81 | CETP (0.32) | CETPCBLB | |
| SCHEMBL30792037 | 0.81 | CETP (0.34) | CETPMAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL30152692 | 0.81 | CETP (0.34) | CETPMAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL29190059 | 0.80 | CETP (0.37) | CETPCBLBMAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4637749-A2 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137674-A2 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2024-06-27 | — | — | WO | disclosed |