Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGPL1 | O95470 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 3/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18130125 | 0.98 | SGPL1 (0.49) | SGPL1LMNAFDPSDNM1LAP3 | |
| SCHEMBL15684353 | 0.83 | SGPL1 (0.43) | SGPL1FDPSDNM1OPRM1 | |
| SCHEMBL21827757 | 0.81 | SGPL1 (0.44) | SGPL1LMNAFDPSDNM1TSHR | |
| SCHEMBL28664154 | 0.81 | SGPL1 (0.44) | SGPL1LMNAFDPSDNM1TSHR | |
| SCHEMBL14848265 | 0.81 | SGPL1 (0.44) | SGPL1LMNAFDPSDNM1TSHR | |
| SCHEMBL13637149 | 0.81 | SGPL1 (0.44) | SGPL1LMNAFDPSDNM1TSHR | |
| SCHEMBL15524956 | 0.81 | SGPL1 (0.44) | SGPL1LMNAFDPSDNM1TSHR | |
| SCHEMBL19705337 | 0.79 | SGPL1 (0.42) | SGPL1LMNAFDPSDNM1TSHR | |
| SCHEMBL16228093 | 0.79 | SGPL1 (0.42) | SGPL1LMNAFDPSDNM1TSHR | |
| SCHEMBL18828735 | 0.79 | SGPL1 (0.42) | SGPL1LMNAFDPSDNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118234492-A | Pharmaceutical composition for preventing or treating alopecia areata with function of functional inhibitor for S1PR1 and S1PR4 | 次代生物科学株式会社 | 2024-06-21 | — | — | CN | disclosed |